Table 2.
Ten most upregulated lncRNAs in HUVECs upon pravastatin (10 µM) stimulation in comparison to controls
| Top 10 upregulated differentially expressed lncRNAs in Statin‐treated versus Control endothelial cells | ||||||
|---|---|---|---|---|---|---|
| Nr | Gene symbol | Fold change | Adj. p‐value | Associated gene | RNA length | Chr/ Strand |
| 1 | LINC00281 | 7.5390834 | .0476663 | 3,215 | 22/− | |
| 2 | AK125078 | 7.2998619 | .0477598 | 847 | 1/‐ | |
| 3 | XLOC_007368 | 6.0619879 | .0209871 | 218 | 9/+ | |
| 4 | XLOC_004244 | 5.5920067 | .0383514 | 690 | 5/+ | |
| 5 | RP11‐469H8.6 | 5.1033278 | .0296308 | AQP2 | 592 | 12/‐ |
| 6 | RP11‐493L12.2 | 4.5832587 | .046438631 | PCED1B | 359 | 12/‐ |
| 7 | RP11‐983C2.2 | 4.5736328 | .026541316 | 482 | 16/‐ | |
| 8 | RP11‐473M20.9 | 4.3979907 | .04118165 | IL32 | 1,207 | 2/‐ |
| 9 | XLOC_001747 | 4.1675991 | .003911454 | 383 | 5/+ | |
| 10 | XLOC_005737 | 4.0376803 | .032008961 | RUNX2 | 2,243 | 6/‐ |
Abbreviations: Adj, Adjusted; AQP2, Aquaporin 2; IL32, Interleukin 32; PCED1B, PC‐Esterase Domain Containing 1B; RUNX2, Runt‐related Transcription Factor 2.