Table 3.
Ten most downregulated lncRNAs in HUVECs upon pravastatin (10 µM) stimulation in comparison to controls
| Top 10 downregulated differentially expressed lncRNAs in Statin‐treated versus Control endothelial cells | ||||||
|---|---|---|---|---|---|---|
| Nr | Gene symbol | Fold change | Adj. p‐value | Associated gene | RNA length | Chr/ Strand |
| 1 | BC045663 | 3.3799237 | .0045743 | 1823 | 20/‐ | |
| 2 | RP11‐876N24.2 | 3.1491515 | .0122195 | CIITA | 575 | 16/‐ |
| 3 | XLOC_001373 | 3.0753019 | .0146288 | 387 | 2/+ | |
| 4 | RP11‐791G16.2 | 3.0002025 | .0156631 | TMEM150C | 1,493 | 4/‐ |
| 5 | RPS11P6 | 2.9800209 | .0091166 | C12orf56 | 1,352 | 12/+ |
| 6 | XLOC_008645 | 2.8372396 | .000696542 | 310 | 10/+ | |
| 7 | UTY | 2.8021482 | .00069716 | UTY | 6,761 | Y/‐ |
| 8 | AC009948.5 | 2.7780046 | .00671064 | PRKRA | 563 | 2/+ |
| 9 | REV3L‐IT1 | 2.7320222 | .038811723 | REV3L | 382 | 6/‐ |
| 10 | RP11‐542B15.1 | 2.6786082 | .034661639 | 559 | 12/+ | |
Abbreviations: Adj, Adjusted; C12orf56, Chromosome 12 Open Reading Frame 56; CIITA, Major Histocompatibility Complex Class II, Transactivator; PRKRA, Protein Kinase, Interferon‐Inducible Double‐Stranded RNA‐Dependent Activator; REV3L, Rev3, S. Cerevisiae, Homolog Of; TMEM150C, Transmembrane Protein 150C; UTY, Ubiquitously Transcribed Tetratricopeptide Repeat Gene on Y Chromosome.