Table 4.
Validation was performed for selected top up or downregulated lncRNAs and mRNAs isolated from HUVECs upon pravastatin (10 µM) stimulation and controls
| Nr | Gene symbol |
Array Data (Fold change) |
p‐value (Adj) |
qPCR Data (Fold change) |
p‐value |
|---|---|---|---|---|---|
| 1 | RP11‐469H8.6 | 5.1033278 | .0296308 | 4.42 ± 1.48 | .002 |
| 2 | BC045663 | −3.3799237 | .0045743 | 0.288 ± 0.177 | .001 |
| 3 | RP11‐791G16.2 | −3.0002025 | .0156631 | 0.399 ± 0.008 | .000 |
| 4 | AC009948.5 | −2.7780046 | .00671064 | 0.669 ± 0.050 | .018 |
| 5 | DMKN | 10.4331054 | .020871174 | 5.49 ± 1.19 | .001 |
| 6 | PIEGO2 | 7.7281947 | .036009804 | 1.755 ± 0.428 | .033 |
| 7 | APOLD1 | 7.4822837 | .00441241 | 1.296 ± 0.179 | .020 |
| 8 | ABI1 | −4.6038017 | .018848386 | 0.643 ± 0.179 | .044 |
| 9 | SND1 | −4.4388801 | .004988181 | 0.813 ± 0.431 | .436 |
| 10 | TMED2 | −4.135675 | .013520699 | 1.174 ± 0.367 | .344 |
| 11 | SCAF8 | −3.7269421 | .017383289 | 0.728 ± 0.114 | .028 |
| 12 | SNX10 | −3.566869 | .001821224 | 0.536 ± 0.313 | .022 |
The “‐” sign indicates downregulation and qPCR data are presented as mean ± SD.