Table 5.
Ten most upregulated mRNAs in HUVECs upon pravastatin (10 µM) stimulation in comparison to controls
| Top 10 upregulated differentially expressed mRNAs in Statin‐treated versus Control endothelial cells | |||
|---|---|---|---|
| Nr | Gene symbol | Fold change | Adj p‐value |
| 1 | DMKN | 10.4331054 | .020871174 |
| 2 | TNNT2 | 8.1375169 | .035583326 |
| 3 | PIEZO2 | 7.7281947 | .036009804 |
| 4 | APOLD1 | 7.4822837 | .00441241 |
| 5 | C7orf34 | 6.5808857 | .044510939 |
| 6 | EIF2B4 | 6.1793913 | .045905061 |
| 7 | TMEM191B | 6.0818645 | .027576263 |
| 8 | ENTHD2 | 5.685957 | .047950255 |
| 9 | A1CF | 5.5672248 | .03958813 |
| 10 | LOC100287177 | 4.9306594 | .032827533 |
Abbreviations: A1CF, Apobec1 Complementation Factor; Adj, Adjusted; APOLD1, Apolipoprotein L Domain‐Containing 1; C7orf34, Chromosome 7 Open Reading Frame 34; DMKN, Dermokine; EIF2B4, Eukaryotic Translation Initiation Factor 2b, Subunit 4; PIEZO2, Piezo‐Type Mechanosensitive Ion Channel Component 2; TMEM191B, Transmembrane Protein 191B; TNNT2, Troponin T2, Cardiac.