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. 2020 Dec 28;128(12):125002. doi: 10.1289/EHP7215

Figure 2.

Figure 2 is a flow diagram having three steps. Step 1: Environmental Conditions, Treatments, and Exposures Ontology, including stressor, medium, and route; disease; gene; and phenotype are interconnected with each other. Step 2: Environmental Conditions, Treatments, and Exposures Ontology, including stressor, medium, and route is connected to receptor. Step 3: Receptor is connected to gene.

Semantic model for representing environmental exposures. Exposure events (open box, represented by terms in the ECTO) can be incorporated into the Monarch knowledge graph via direct links to the diseases and phenotypes resulting from the exposure, the genes being affected, and the organism(s) or organism parts that are being exposed. Note: ECTO, Environmental Conditions, Treatments, and Exposures Ontology.