| Level 3 | In children (with Crouzon syndrome and an average age of 18 to 24 months), starting treatment for signs of elevated ICP may result in a surgical indication in at least 61%. With protocol-based treatment, regardless of the presence of elevated ICP, possibly 83% of patients will be operated on at mean age 18 months. B Spruijt et al, 2016; C Abu-Sittah et al, 2016 |
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