Table 3:
Association of quinolinic acid and functional connectivity strength in SRC+
| Region-of-Interest | Beta | SE | t | df | p-value | FDR-corrected p |
|---|---|---|---|---|---|---|
| Pallidum_R | 27.66 | 7.18 | 3.85 | 43.12 | < 0.001 | < 0.001 |
| Caudate_L | 25.80 | 6.77 | 3.81 | 31.45 | 0.001 | 0.017 |
| Olfactory_L | 25.55 | 7.37 | 3.47 | 45.39 | 0.001 | 0.017 |
| Caudate_R | 25.30 | 7.22 | 3.51 | 46.09 | 0.001 | 0.017 |
| Olfactory_R | 25.04 | 7.38 | 3.39 | 39.94 | 0.002 | 0.018 |
| Heschl_L | 24.69 | 7.64 | 3.23 | 42.42 | 0.002 | 0.018 |
| Frontal_Med_Orb_L | 24.67 | 6.76 | 3.65 | 55.46 | 0.001 | 0.017 |
| Frontal_Sup_2_R | 24.16 | 7.08 | 3.41 | 56.49 | 0.001 | 0.017 |
| Frontal_Med_Orb_R | 23.62 | 7.01 | 3.37 | 47.39 | 0.001 | 0.017 |
| Insula_L | 22.00 | 7.22 | 3.05 | 40.95 | 0.004 | 0.030 |
| Putamen_L | 21.98 | 6.79 | 3.24 | 44.81 | 0.002 | 0.018 |
| Frontal_Sup_Medial_L | 21.68 | 7.33 | 2.96 | 51.57 | 0.005 | 0.034 |
| Putamen_R | 20.95 | 6.38 | 3.28 | 44.35 | 0.002 | 0.018 |
| Cingulate_Ant_R | 20.53 | 7.16 | 2.87 | 47.68 | 0.006 | 0.034 |
| Rectus_R | 20.46 | 6.74 | 3.04 | 47.94 | 0.004 | 0.030 |
| Insula_R | 19.68 | 7.14 | 2.76 | 33.43 | 0.009 | 0.043 |
| Paracentral_Lobule_L | 19.54 | 7.47 | 2.62 | 48.54 | 0.012 | 0.046 |
| OFCmed_R | 19.50 | 5.87 | 3.32 | 34.07 | 0.002 | 0.018 |
| Cerebellum_9_R | 19.42 | 6.06 | 3.21 | 60.94 | 0.002 | 0.018 |
| Rolandic_Oper_L | 19.33 | 6.85 | 2.82 | 32.92 | 0.008 | 0.042 |
| Precuneus_L | 19.10 | 7.06 | 2.70 | 48.82 | 0.009 | 0.043 |
| Frontal_Sup_2_L | 19.05 | 6.66 | 2.86 | 47.02 | 0.006 | 0.034 |
| ParaHippocampal_L | 18.99 | 6.55 | 2.90 | 44.99 | 0.006 | 0.034 |
| OFCpost_R | 18.93 | 6.98 | 2.71 | 36.45 | 0.010 | 0.044 |
| Occipital_Mid_L | 18.90 | 6.67 | 2.83 | 52.81 | 0.006 | 0.034 |
| Calcarine_R | 18.88 | 6.75 | 2.80 | 45.16 | 0.008 | 0.042 |
| Angular_R | 18.72 | 7.22 | 2.59 | 59.77 | 0.012 | 0.046 |
| Lingual_L | 18.64 | 7.12 | 2.62 | 44.09 | 0.012 | 0.046 |
| Lingual_R | 18.63 | 7.00 | 2.66 | 51.31 | 0.010 | 0.044 |
| Cerebellum_Crus2_L | 17.52 | 5.81 | 3.02 | 44.48 | 0.004 | 0.030 |
| Cerebellum_Crus1_L | 17.10 | 6.58 | 2.60 | 52.82 | 0.012 | 0.046 |
Note: Shown are the parameter estimates for the significant associations between natural log transformed quinolinic acid and connectivity strength for specific regions-of-interest from the Automated Anatomical Labeling (version 2) atlas following False Discovery Rate (FDR) correction. SE = standard error, df = degrees of freedom, t = t statistic, _R = right hemisphere, _L = left hemisphere, Med = medial, Orb = orbital, Sup = superior, Ant = anterior, Oper = operculum, Post = posterior, Mid = middle, OFC = orbitofrontal cortex.