Table 2. Univariate analysis comparing cancer patients who did and did not develop sepsis within 1 year of cancer diagnosis.
| No sepsis | Sepsis | p value | |
|---|---|---|---|
| (n = 115011) | (n = 4368) | ||
| Age (years) | 55 (49–59) | 57 (51–60) | < 0.001 |
| Male gender, n (%) | 44199 (38.4%) | 2248 (51.5%) | < 0.001 |
| CCI 1–2, n (%) | 32731 (29.1%) | 1647 (38.8%) | < 0.001 |
| CCI >2, n (%) | 3884 (3.5%) | 348 (8.2%) | < 0.001 |
| Metastases at diagnosis, n (%) | 12064 (10.5%) | 718 (16.4%) | < 0.001 |
| Myocardial infarction, n (%) | 891 (0.8%) | 46 (1.1%) | 0.037 |
| Congestive heart failure, n (%) | 1539 (1.4%) | 126 (3.0%) | < 0.001 |
| Peripheral vascular disease, n (%) | 2815 (2.5%) | 185 (4.4%) | < 0.001 |
| Cerebrovascular disease, n (%) | 3123 (2.8%) | 180 (4.2%) | < 0.001 |
| Dementia, n (%) | 41 (<0.1%) | 1 (<0.1%) | 0.663 |
| Chronic pulmonary disease, n (%) | 12049 (10.7%) | 635 (15.0%) | < 0.001 |
| Rheumatic disease, n (%) | 2327 (2.1%) | 104 (2.4%) | 0.090 |
| Mild liver disease, n (%) | 5634 (5.0%) | 427 (10.1%) | < 0.001 |
| Diabetes without chronic complication, n (%) | 16217 (14.4%) | 908 (21.4%) | < 0.001 |
| Diabetes with chronic complication, n (%) | 2297 (2.0%) | 168 (4.0%) | < 0.001 |
| Hemiplegia or paraplegia, n (%) | 216 (0.2%) | 15 (0.4%) | 0.021 |
| Renal disease, n (%) | 1672 (1.5%) | 167 (3.9%) | < 0.001 |
| Moderate or severe liver disease, n (%) | 372 (0.3%) | 43 (1.0%) | < 0.001 |
| AIDS / HIV, n (%) | 362 (0.3%) | 40 (0.9%) | < 0.001 |
| Cancer site, n (%) | < 0.001 | ||
| digestive | 17751 (15.4%) | 1108 (25.4%) | |
| genitourinary | 16211 (14.1%) | 395 (9.0%) | |
| head and neck | 2091 (1.8%) | 87 (2.0%) | |
| hematological malignancy | 10049 (8.7%) | 796 (18.2%) | |
| Musculoskeletal/breast | 36786 (32.0%) | 512 (11.7%) | |
| other site | 23219 (20.2%) | 987 (22.6%) | |
| respiratory system | 8904 (7.7%) | 483 (11.1%) |
CCI: Charlson comorbidity index.