Table 3.

MRI characteristics of the included studies.

Study	Sequence	Parameter	Field strength (T)	Contrast agent	Contrast injection rate	Threshold
Xintao Hu 2011[13]	DSC (SVM)	normalized rCBV	UN	UN	UN	rCBV>1.14
Ramon F 2009[14]	DSC	normalized rCBV	1.5	Gadopentetate 0.1 mmol/kg	5ml/s	rCBV>1.75
J.Cha 2014[15]	DSC	normalized rCBV	3.0	Gadopentetate 0.1 mmol/kg	UN	rCBV>1.8
Ho Sung Kim 2010[16]	DSC	max rCBV	3.0	Gadopentetate 0.1 mmol/kg	4mL/s	rCBVmax>2.6
Doo-Sik Kong 2011[17]	DSC	normalized rCBV	3.0	Gadobutrol 0.1 mmol/kg	4mL/s	rCBV>1.47
L.S. Hu 2009[18]	DSC	normalized rCBV	3.0	Gadodiamide 0.15 mmol/kg	3-5mL/s	rCBV>0.71
Tae-Hyung Kim 2017[19]	DSC	normalized rCBV	3.0	Gadobutrol 0.1 mmol/kg	4mL/s	rCBV>1.07
Achim Seeger 2013[20]	DSC/DCE	normalized rCBV/K trans	1.5	Gadobutrol 0.1 mmol/kg	3mL/s	rCBV>1.14 Ktrans>0.058
S. Wang 2016[21]	DSC	max rCBV	3.0	Gadopentetate 0.07 mmol/kg	5mL/s	rCBVmax>4.06
Yu-Lin Wang 2018[22]	DSC/ASL	normalized rCBV/rCBF	3.0	Gadolinium 0.1 mmol/kg	4mL/s	rCBV>2.86 rCBF>1.86
Nisha Rani 2018[23]	DSC	normalized rCBV	1.5 or 3.0	Gadopentetate 0.1 5mmol/kg	3-5mL/s	rCBV>2.12
A.J. Prager 2015[24]	DSC	normalized rCBV	1.5 or 3.0	Gadopentetate 0.07mmol/kg	5mL/s	rCBV>1.27
Kambiz Nael 2018[25]	DSC/DCE	normalized rCBV/K-trans	1.5 or 3.0	Gadopentetate 0.15mmol/kg	5mL/s	rCBV>2.2 K-trans(min−1) >0.1
Nader Zakhari 2019[26]	DSC/DCE	normalized rCBV/K-trans	3.0	UN	UN	rCBV>2.74 K-trans(min−1) >0.07
Young Jun Choi 2013[27]	DSC/ASL	normalized rCBV/rCBF	3.0	Gadopentetate 0.1 mmol/kg	4mL/s	UN/UN
Heba M. Soliman 2018[28]	DSC	normalized rCBV	1.5	Dotarem 0.1 mmol/kg	UN	rCBV>1.8
Qian Xu 2017[29]	DSC/ASL	normalized rCBV/rCBF	3.0	Gadopentetate 0.2 mmol/kg	3mL/s	rCBV>3.64 rCBF<1.11
Z. Qiao 2019[30]	DSC	normalized rCBV	UN	UN	UN	rCBV>1.83
Eike Steidl 2019[31]	DSC	max rCBV	3.0	Gadovist 0.1 mmol/kg	4mL/s	rCBV>2.75
Nabil Elshafeey 2019[32]	DSC/DCE (SVM)	normalized rCBV/K-trans	3.0	UN	UN	SVM models