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. 2020 Dec 28;15(12):e0244477. doi: 10.1371/journal.pone.0244477

Table 1. Clinical, demographic and exposure comparison between healthcare workers and non-healthcare workers with SARS-CoV-2 infection (n = 56,606).

Variable Healthcare workers, n (%) Non-healthcare workers, n (%) p-valuea
Doctor Nurse Otherb Total
Total (% of all SARS-CoV-2 infections) 161 (0.3) 1756 (3.1) 5133 (9.1) 7050 (12.5) 49556 (87.5)
Female gender 65 (40.4) 1516 (86.3) 4142 (80.7) 5723 (81.2) 23479 (47.4) <0.001
Age <0.001
    <30 25 (15.5) 443 (25.2) 890 (17.3) 1358 (19.3) 15107 (30.5)
    30–44 68 (42.2) 630 (35.9) 1603 (31.2) 2301(32.6) 10153(20.5)
    45–59 36 (22.4) 557 (31.7) 2057 (40.1) 2650 (37.6) 9581 (19.3)
    60–74 29 (18.0) 125 (7.1) 576 11.2) 730 (10.4) 6630 (13.4)
    75+ 3 (1.9) 1 (0.1) 7 (0.1) 11 (0.2) 8079 (16.3)
    Unknown 0 0 0 0 6 (<0.1)
One or more comorbiditiesc 36 (22.4) 537 (30.6) 1482 (28.9) 2055 (29.1) 14073 (28.4) 0.19
    Asthma 8 (5.0) 123 (7.0) 327 (6.4) 458 (6.5) 2197 (4.4)
    COPD 0 7 (0.4) 8 (0.2) 15 (0.2) 669 (1.3)
    Renal conditions 1 (0.6) 9 (0.5) 39 (0.8) 49 (0.7) 1020 (2.1)
    Cardiovascular conditions 13 (8.1) 163 (9.3) 457 (8.9) 633 (9.0) 6012 (12.1)
    Diabetes 5 (3.1) 108 (6.2) 364 (7.1) 477 (6.8) 3988 (8.0)
    Immune compromised or cancer 3 (1.9) 45 (2.6) 132 (2.6) 180 (2.6) 1693 (3.4)
    Obesity 1 (0.6) 43 (2.4) 89 (1.7) 133 (1.9) 589 (1.2)
    Other medical conditions 13 (8.1) 249 (14.2) 578 (11.3) 840 (11.9) 6274 (12.7)
Clinical presentation
    Presymptomatic 1 (0.6) 30 (1.7) 77 (1.5) 108 (1.5) 601 (1.2) 0.02
    Presenting symptoms <0.001
        Asymptomatic 19 (11.8) 177 (10.1) 951 (18.5) 1147 (16.3) 8680 (17.5)
        Fever and/or cough 90 (55.9) 981 (55.9) 2578 (50.2) 3802 (53.9) 23165 (46.7)
        Other symptoms 32 (19.9) 427 (24.3) 1359 (26.5) 1906 (27.0) 12918 (26.1)
        Missing symptom data 4 (2.5) 40 (2.3) 220 (4.3) 195 (2.8) 4793 (9.7)
Outcomes <0.001
        Not hospitalized 150(93.2) 1687 (96.1) 4966 (96.7) 6803 (96.5) 42713 (86.2)
        Hospitalized 7 (4.3) 51 (2.9) 121 (2.4) 179 (2.5) 3128 (6.3)
        Intensive care unit—not on ventilator 1 (0.6) 10 (0.6) 30 (0.6) 41 (0.6) 500 (1.0)
        Intensive care unit–on a ventilator 3 (1.9) 7 (0.4) 5 (0.1) 15 (0.2) 211 (0.4)
        Died 0 1 (0.1) 11 (0.2) 12 (0.2) 3004 (6.1)
Resolved 161 (100.0) 1752 (99.8) 5109 (99.5) 7022 (99.6) 45737 (92.3) <0.001
Exposure history <0.001
        Outbreak-associated or close contact of a confirmed case 67 (41.6) 1347 (76.7) 3956 (77.1) 5370 (76.2) 31268 (63.1)
        No known epidemiological link 57 (35.4) 291 (16.6) 835 (16.3) 1183 (16.8) 8281 (16.7)
        Travel-Related 28 (17.4) 77 (4.4) 152 (3.0) 257 (3.6) 1997 (4.0)
        Information missing 9 (5.6) 41 (2.3) 190 (3.7) 240 (3.4) 8010 (16.2)
Exposed to long-term care home 6 (3.7) 586 (33.4) 2334 (45.5) 2926 (41.5) 6926 (14.0)
Nosocomial transmissiond <0.001
        Yes 1 (0.9) 80 (5.1) 106 (2.3) 187 (3.0) 410 (0.9)
        No 33 (30.3) 301 (19.0) 820 (18.0) 1154 (18.4) 6523 (14.1)
        Unknown or missing 75 (68.8) 1201 (75.9) 3642 (79.7) 4918 (78.6) 39490 (85.1)

a Statistical comparison between total healthcare workers and non-healthcare workers

b 2154 (30.6%) were personal support workers identified through free text searching.

c Comorbidities include; anemia or hemoglobinopathy, asthma, cancer, cardiovascular disease, chronic liver disease, chronic obstructive pulmonary disease (COPD), diabetes, immunocompromised, neurological disorder, obesity, pregnant or post-partum, renal conditions, tuberculosis, other chronic medical condition.

d Nosocomial variable added on April 3, 2020, therefore the denominators used were 6259 healthcare workers (109 doctors, 1582 nurses, and 4568 other) and 46423 non-healthcare workers.