Table 3.
Detailed results per site
| Site | Multiparametric MRI | Micro-ultrasound | n | ||||||
|---|---|---|---|---|---|---|---|---|---|
|
|
|
||||||||
| True positive | True negative | False positive | False negative | True positive | True negative | False positive | False negative | ||
| A | 70 | 46 | 64 | 14 | 84 | 13 | 97 | 0 | 194 |
| B | 3 | 1 | 5 | 0 | 3 | 0 | 6 | 0 | 9 |
| C | 97 | 22 | 163 | 10 | 97 | 44 | 141 | 10 | 292 |
| D | 9 | 7 | 1 | 2 | 10 | 2 | 6 | 1 | 19 |
| E | 76 | 5 | 76 | 2 | 74 | 12 | 69 | 4 | 159 |
| F | 20 | 9 | 20 | 2 | 22 | 5 | 24 | 0 | 51 |
| G | 24 | 13 | 38 | 2 | 25 | 9 | 42 | 1 | 77 |
| H | 29 | 27 | 53 | 7 | 31 | 24 | 56 | 5 | 116 |
| I | 19 | 3 | 25 | 0 | 17 | 8 | 20 | 2 | 47 |
| J | 21 | 1 | 40 | 0 | 19 | 21 | 20 | 2 | 62 |
| K | 3 | 2 | 8 | 1 | 4 | 0 | 10 | 0 | 14 |
| Total | 371 | 136 | 493 | 40 | 386 | 138 | 491 | 25 | 1040 |
While clear site-level variability is seen on targeting percentage and accuracy, only 3 sites (B, I, J) failed to achieve non-inferior sensitivity on their own. Aggregate results demonstrate superior sensitivity for micro-ultrasound (p=0.03) and non-inferior specificity (p<0.01). MRI: magnetic resonance imaging.