Table 2.
Pathologic features on renal biopsies of 193 patients
| Method | Pathologic features | Number of patients | Percentage of patients |
|---|---|---|---|
| Light microscopy | FSGS | 68/193 | 35.2 |
| MPGN | 10/193 | 5.2 | |
| IgA nephropathy | 1/193 | 0.5 | |
| Electron microscopy | Thinning of GBM | 141/174 | 81 |
| Thickening of GBM | 32/174 | 18.4 | |
| Splitting of GBM | 28/174 | 16.1 | |
| Lamination of GBM | 12/174 | 6.9 | |
| Wrinkling of GBM | 3/174 | 1.7 | |
| Basket weaving of GBM | 10/174 | 5.8 | |
| Foot process effacement | 12/174 | 6.9 | |
| Immunofluorescence | Positive for IgA, IgG, IgM, C1q, C3, Fib | 17/41 | 41.5 |
| Immunohistochemistry | Positive for α5 | 28/31 | 90.3 |
fib, fibrinogen.