Table 2. Multivariate COX proportional regression analysis of need of high-flow oxygen support in the training cohort.
| Multivariate analysis | ||
|---|---|---|
| HR (95% CI) | p value | |
| Male sex | -- | 0.873 |
| Age, years | -- | 0.705 |
| Arterial Hypertension | -- | 0.327 |
| Diabetes mellitus | -- | 0.464 |
| Obesity | 2.393 (1.103–5.193) | 0.027 |
| COPD | -- | 0.192 |
| Smoker (active or former) | -- | 0.438 |
| Immunosuppresive therapy | 4.008 (1.331–12.073) | 0.014 |
| X-ray (peripheral infiltrate as reference) | ||
| Unilateral pneumonia | 2.057 (1.410–3.001) | <0.001 |
| Bilateral pneumonia | ||
| SpO2/FiO2 | 3.495 (2.012–6.070) | <0.001 |
| Fever | -- | 0.535 |
| Dyspnea | -- | 0.596 |
| Diarrhea | -- | 0.061 |
| Mialgya | -- | 0.467 |
| Hemoglobin, mg/dL | -- | 0.430 |
| Neutrophils/ Lymphocyte ratio | -- | 0.483 |
| Platelets, x10E9/L | 0.436 (0.216–0.882) | 0.021 |
| Ferritin, ng/mL | -- | 0.645 |
| C reactive protein, mg/dL | -- | 0.485 |
| LDH, IU/dL | -- | 0.998 |
| Urea, mg/dL | -- | 0.608 |
| IL-6, pg/mL | 2.891 (1.430–5.843) | 0.003 |