Table 4.
Patients and tumor characteristics of forkhead box P3 negative vs positive
|
Variables
|
Characteristics
|
FOXP3 negative 75 (75.0%)
|
FOXP3 positive 25 (25.0%)
|
P
value
|
| Age (yr) | mean ± SD | 48.60 ± 11.02 | 47.32 ± 14.20 | 0.64 |
| IDO score | Low | 22 (91.7%) | 2 (8.3%) | 0.01a |
| Medium | 23 (85.2%) | 4 (14.8%) | ||
| High | 30 (61.2%) | 19 (38.8%) | ||
| Grade | II | 28 (80.0%) | 7 (20.0%) | 0.21 |
| III | 38 (67.9%) | 18 (32.1%) | ||
| Metastasis | Negative | 27 (71.1%) | 11 (28.9%) | 0.45 |
| Positive | 39 (79.6%) | 10 (20.4%) | ||
| Tumor size | T1 | 4 (57.1%) | 3 (42.9%) | 0.15 |
| T2/T3 | 46 (80.7%) | 11 (19.3%) | ||
| Lymph nodes involvement | Negative | 26 (70.3%) | 11 (29.7%) | 0.29 |
| Positive | 40 (80.0%) | 10 (20.0%) | ||
| Estrogen receptor | Negative | 48 (69.6%) | 21 (30.4%) | 0.06 |
| Positive | 27 (87.1%) | 4 (12.9%) | ||
| Progesterone receptor | Negative | 52 (70.3%) | 22 (29.7%) | 0.06 |
| Positive | 23 (88.5%) | 3 (11.5%) | ||
| HER2–neu receptor | Negative | 53 (71.6%) | 21 (28.4%) | 0.19 |
| Positive | 22 (84.6%) | 4 (15.4%) | ||
| Triple negative breast cancer | No | 44 (86.3%) | 7 (13.7%) | 0.01a |
| Yes | 31 (63.3%) | 18 (36.7%) |
a
P < 0.05. IDO: Indoleamine 2,3-dioxygenase; HER2: Human epidermal growth factor receptor; FOXP3: Forkhead box P3; SD: Standard deviation.