Table 4.
Clinical characteristics of combination low alpha-fetoprotein/gamma glutamyl transpeptidase patients vs all other combinations
| Parameters | Low AFP ≤ 200, low GGT ≤ 104, n = 14 | Other combos, n = 34 | P value |
| AFP (ng/mL) | |||
| Median | 7.35 | 132.5 | 0.009b |
| mean ± SD | 21.6 ± 32.4 | 758.5 ± 2397.2 | |
| GGT (IU/L) | |||
| Median | 63 | 140.5 | < 0.001c |
| mean ± SD | 59.6 ± 31.6 | 208.9 ± 232.4 | |
| Total Bilirubin (mg/dL) | |||
| Median | 2 | 1.4 | 0.511 |
| mean ± SD | 3.2 ± 3.8 | 2.5 ± 3.0 | |
| AST (IU/L) | |||
| Median | 68.5 | 77.5 | 0.892 |
| mean ± SD | 126.2 ± 145.9 | 93.2 ± 66.4 | |
| MTD (cm) | |||
| Median | 8.75 | 8.25 | 0.317 |
| mean ± SD | 8.66 ± 1.18 | 9.9 ± 4.5 | |
| Number of nodules, n (%) | |||
| 1 | 8 (57) | 14 (41) | 0.490 |
| > 1 | 6 (43) | 20 (59) | |
| Microvascular invasion, n (%) | |||
| Negative | 7 (50) | 7 (21) | 0.041a |
| Positive | 7 (50) | 27 (79) | |
| Differentiation, n (%) | |||
| Well | 7 (50) | 7 (20) | 0.020a |
| Moderate | 5 (36) | 19 (56) | |
| Poor | 2 (14) | 8 (24) |
a
P < 0.05.
b
P < 0.01.
c
P < 0.001.
AFP: Alpha-fetoprotein; GGT: Gamma glutamyl transpeptidase; AST: Aspartate aminotransferase; MTD: Maximum dominant tumor diameter; SD: Standard deviation.