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. 2020 Dec 15;11:590683. doi: 10.3389/fmicb.2020.590683

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Copyright © 2020 Rezasoltani, Yadegar, Hatami, Asadzadeh Aghdaei and Zali.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Negative impact of high-concentration release of different kinds of biocides and antibiotics in the environment, which may result in antibiotic resistance enrichment and resistance dissemination. It is presumed that during the COVID-19 pandemic, these antimicrobials are excessively released in the soil and manure, surface and underground water, food, plants and crops, and terrestrial and aquatic animals. On the other hand, enrichment of biocide and antibiotic concentrations at the sub-minimum inhibitory concentration (sub-MIC) in the environment may augment the selective pressure phenomenon, boost the horizontal gene transfer (HGT), and drive the evolution of antimicrobial resistance (AMR) that lead to the selection of antibiotic-resistant bacteria. Therefore, current management practices and strategies to prevent and control AMR should be extremely highlighted in relation to the COVID-19 outbreak.