Table 1.
Daily clinical pattern of the patient.
Parameter, Units | Day 0 | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 | Day 7 | Day 8 | Day 9 | Day 10 | Day 11 | Day 12 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PE, circulating plasma volumes | 2 | 1 | |||||||||||
CytoSorb, hours | 12 | ![]() |
|||||||||||
Toraymyxin PMX-20R, hrs | ![]() |
8 | 8 | ||||||||||
HR, bpm | 125 | 135 | 139 | 155 | 119 | 86 | 102 | 87 | 78 | 115 | 110 | 100 | 125 |
CVP, mmHg | 35 | 24 | 14 | 14 | 14 | 15 | 14 | 15 | 14 | 14 | 12 | 10 | 13 |
Systolic BP, mmHg | 84 | 95 | 73 | 84 | 64 | 92 | 77 | 112 | 91 | 116 | 108 | 125 | 124 |
Diastolic BP, mmHg | 57 | 78 | 47 | 58 | 40 | 51 | 55 | 61 | 57 | 79 | 64 | 73 | 84 |
MAP, mmHg | 69 | 83 | 58 | 70 | 49 | 65 | 63 | 83 | 64 | 97 | 83 | 86 | 85 |
Dopamine, mcg/kg/min | 15 | 15 | 15 | 6 | 5 | 8 | 5 | 7 | 7 | 7 | 5 | 6 | |
Norepinephrine, mcg/kg/min | 0,8 | 0,4 | 0.05 | ||||||||||
Epinephrine, mcg/kg/min | 0.6 | 0.25 | 0.7 | 0.2 | 0 | 0.08 | 0.02 | 0.03 | 0.03 | 0.04 | |||
Vasoactive inotrope support (VIS) index | 75 | 40 | 165 | 66 | 10 | 16 | 7 | 7 | 7 | 10 | 9 | ||
ECMO flow, ml/min | 510 | 460 | 710 | 780 | 850 | 270 | 220 | ||||||
ECMO, rotations per minute | 5,900 | 5,150 | 4,550 | 4,800 | 4,600 | 3,550 | 3,450 | ||||||
Flow index L/min/m2 | 1.5 | 1.35 | 2.08 | 2.29 | 2.5 | 0.8 | 0.64 | ||||||
RBC, units (1 unit−100 ml) | 2 | 1 | 1 | 1 | 1 | 1 | |||||||
FFP, units (1 unit−120 ml) | 1 | 1 | 1 | 1 | |||||||||
Brain NIRS right hemisphere, % | 60 | 64 | 65 | 64 | 78 | 79 | 81 | ||||||
Brain NIRS left hemisphere, % | 61 | 62 | 82 | 83 | 91 | 90 | 92 | ||||||
Transplant NIRS, % | 74 | 81 | 90 | 91 | |||||||||
Hb, g/L | 72 | 84 | 76 | 63 | 69 | 97 | 100 | 66 | 60 | 89 | 75 | 76 | |
WBC, × 109/L | 1.25 | 9.63 | 15.48 | 7.89 | 9.26 | 7.55 | 7.54 | 9.99 | 10.45 | 11.97 | 21.18 | 19.32 | |
Platelets, × 109/L | 11 | 79 | 29 | 6 | 7 | 12 | 7 | 13 | 10 | 12 | 13 | 13 | |
ALT, IU/L | 20.5 | 2108.7 | 914.6 | 273.5 | 21 | 70.9 | 30.9 | 20 | 17.1 | 15.4 | 13.2 | 10 | 7.9 |
AST, IU/L | 31.9 | 3172.4 | 4038.3 | 1291.5 | 265.4 | 647.3 | 237.9 | 97.9 | 60.4 | 50.6 | 46 | 37.2 | 24.5 |
Albumin, g/L | 28.7 | 10.2 | 31.7 | 14.9 | 21.4 | 26.6 | 35 | 26 | 22.3 | 22.5 | 19.7 | 22.6 | 25.7 |
Creatinine, mmol/L | 340 | 95 | 95 | 86 | 20 | 116 | 101 | 85 | 62 | 73 | 78 | 57 | 4 |
Urea, mmol/L | 31.19 | 12.72 | 12.25 | 11.82 | 12.26 | 12.68 | 11.5 | 9.52 | 8.73 | 12.13 | 15.22 | 11.86 | 10.08 |
LDH, U/L | 327 | 5,863 | 3,405 | 1,540 | 281 | 1,229 | 907 | 596 | 128 | 92 | 92 | 447 | 405 |
Creatine kinase, U/L | 2,410 | 7,867 | 10,468 | 12,425 | 3,677 | 300 | 509 | 510 | 522 | 58 | 47 | ||
C-reactive protein, mg/L | 15.77 | 8.95 | 109.38 | 67.81 | 128.44 | 137.72 | 129.88 | 97.27 | 1.88 | 64.65 | 126.57 | 128.22 | 62.82 |
Procalcitonin, ng/ml | 3.12 | 6.54 | 9.82 | 0.58 | 3.62 | 3.78 | 5.47 | 2.85 | 2.08 | 91.8 | 47.72 | 19.69 | |
CVVHD filtrate volume, ml/day | 500 | 1,500 | 1,200 | 1,230 | 1,300 | 1,700 | 670 |
D0, day of transplantation; HR, heart rate; CVP, central venous pressure; BP, arterial blood pressure; MAP, mean arterial pressure; ECMO, extracorporeal membrane oxygenation; RBC, red blood cells; FFP, fresh frozen plasma; NIRS, near infrared spectroscopy; Hb, hemoglobin; WBC, white blood cells; ALT, alanine aminotransferase; AST, aspartate aminotransferase; LDG, lactate-dehydrogenase; CVVHD, continuous venovenous hemodialysis; PE, plasma exchange.