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. 2020 Jun 23;98(8):1107–1123. doi: 10.1007/s00109-020-01937-4

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© The Author(s) 2020

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Fig. 5 — Detail analysis of a deletion in Chr.15q14 of two matched patients. Genomic deletion in 15q14, including the GOLGAG8A gene (a). RNA expression analysis using qPCR in 1N8, 2N8, and corresponding 0N11 patients. The analysis was performed with irradiated (2, 5 Gy) and control (0 Gy) cells at 2 h post-treatment (b). qPCR copy number analysis of this region reveals heterozygous deletions of the DNA fragment in a heterozygous state (c)