Segmentations of computed tomography scans at the level of the third lumbar vertebra (L3) in (A) a non-sarcopenic male patient and (B) a sarcopenic male patient. Blue segmentations indicate subcutaneous adipose tissue (sAT), purple segmentations indicate skeletal muscle (SM; paraspinal muscles adjacent to L3 and muscles of the abdominal wall); yellow segmentations indicate visceral adipose tissue [vAT] surrounding the abdominal viscera; and grey/blank segmentations indicate the abdominal organs (including the small and large bowel, liver and kidneys). Segmentation was processed using machine learning software [27]. Clearly, there is little visible difference between some non-sarcopenic and sarcopenic patients, highlighting the importance of segmentation and calculation of SMI values. Abbreviations: SMI, skeletal muscle index.