Figure 3:

(A) Mean aortic flow confirmed the generation of aortic regurgitation in our bicuspid aortic valve (BAV) model at baseline as evidenced by the flow reversal observed in diastole. After repair, the regurgitant fraction was significantly reduced (28.6±3.4% versus 14.5±4.4%, p=.014). (B) Aortic pressure tracings demonstrated significantly lower pressures throughout the cardiac cycle for the BAV model at baseline compared to after repair: mean arterial pressure (81.1±1.2 versus 94.3±1.6mmHg, p<0.001), diastolic pressure (61.7±2.1 versus 76.3±3.6mmHg, p=0.007), and systolic pressure (104.2±0.9 versus 119.1±1.1mmHg, p<0.001). Shaded regions represent standard deviation.