Figure 4.

Morris water maze performance indicated faster swim speeds in iTat mice during acute vs. prolonged HIV-1 Tat expression. (A) Path length and (B) swimming speed were assessed in iTat and WT mice over four sessions. Each data point represents the mean ± SEM from an average of four trials per session. One session is equivalent to 1 day. The WT mice (n = 7, solid line with open circles) and the iTat mice (n = 11, solid line with open squares) received acute induction by DOX i.p. injections, while the WT mice (n = 13, dashed line with solid circles) and the iTat mice (n = 13, dashed line with solid squares) received prolonged induction via DOX food.