Table 1.

MMP/TIMP ratios in acute and prolonged DOX-treated iTat mice injected and fed with DOX, respectively.

Ratio	iTat Inj	iTat Food
	n = 11	n = 13
MMP-9/TIMP-1	0.95 (0.38)	1.24 (0.3)#
MMP-2/TIMP-2	1.26 (0.28)	1.20 (0.2)
MMP-2/TIMP-1	1.05 (0.38)	1.34 (0.25)#
MMP-9/TIMP-2	1.13 (0.32)	1.11 (0.21)

TIMP-1, TIMP-2, MMP-9, and MMP-2 mRNA fold change values presented in Figure 7 were used to obtain the above ratios in iTat mice. The ratios were calculated from the mean of relative fold change calculated for iTat mice, relative to their treatment time matched WT controls. Each row represents the mean ± Standard Deviation

^#p < 0.05 for same Strain comparisons across Treatment Time by one-way ANOVA.