Table 3.
Solubility, transmembrane helices, localisation and antigenicity results predicted by SolPro, TMHMM, Virus-mPLoc and Vaxijen, respectively.
| Proteins | SolPro | TMHMM | Virus-mPLoc | Vaxijen v2.0 value | |
|---|---|---|---|---|---|
| Structural proteins | S protein | Soluble | 1 | Host endoplasmic reticulum | 0.4661 (probable antigen) |
| E protein | Soluble | 1 | Host endoplasmic reticulum | 0.6025 (probable antigen) | |
| M protein | Insoluble | 3 | Host cell membrane, endoplasmic reticulum | 0.5102 (probable antigen) | |
| N protein | Soluble | 0 | Host cell membrane | 0.5059 (probable antigen) | |
| Non-structural proteins | orf3a | Insoluble | 3 | Host cell membrane | 0.4945 (probable antigen) |
| orf6 | Soluble | 0 | Host endoplasmic reticulum | 0.6131 (probable antigen) | |
| orf7a | Soluble | 1 | Host endoplasmic reticulum | 0.6441 (probable antigen) | |
| orf7b | Soluble | 1 | a | 0.8462 (probable antigen) | |
| orf8 | Soluble | 0 | Host cell membrane, endoplasmic reticulum, cytoplasm | 0.6502 (probable antigen) | |
| orf10 | Soluble | 0 | a | 0.7185 (probable antigen) | |
| Pp1ab | nsp-1 | Soluble | 0 | Host cytoplasm | 0.4064 (probable antigen) |
| nsp-2 | Insoluble | 0 | Host cytoplasm | 0.4034 (Probable antigen) | |
| nsp-3 | a | 4 | Host cytoplasm | 0.5142 (probable antigen) | |
| nsp-4 | Insoluble | 4 | Host cell membrane, endoplasmic reticulum | 0.4691 (probable antigen) | |
| nsp-5 | Insoluble | 0 | Host cell membrane | 0.4159 (probable antigen) | |
| nsp-6 | Soluble | 8 | Host cell membrane | 0.5813 (probable antigen) | |
| nsp-7 | Insoluble | 0 | Host cytoplasm | 0.4167 (probable antigen) | |
| nsp-8 | Soluble | 0 | Host cytoplasm | 0.4008 (probable antigen) | |
| nsp-9 | Soluble | 0 | Host cell membrane, cytoplasm | 0.6476 (Probable antigen) | |
| nsp-10 | Insoluble | 0 | Host cell membrane, endoplasmic reticulum | 0.4039 (probable antigen) | |
| nsp-12 | Insoluble | 0 | Host cytoplasm | 0.4064 (probable antigen) | |
| nsp-13 | Insoluble | 0 | Host nucleus | 0.4480 (probable antigen) | |
| nsp-14 | Insoluble | 0 | Host cytoplasm, nucleus | 0.4138 (probable antigen) | |
| nsp-15 | Insoluble | 0 | Host cytoplasm | 0.5554 (probable antigen) | |
| nsp-16 | Insoluble | 0 | Host cytoplasm | 0.3800 (probable non-antigen) |
aCould not be retrieved.