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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Curr Opin Pharmacol. 2020 Sep 6;54:36–43. doi: 10.1016/j.coph.2020.08.006

Figure 1: Bone marrow microenvironment (BMM) is a dynamic and complex network.

Figure 1:

The BMM consists of several cells including quiescent/activated hematopoietic stem cells (HSCs), osteoclast cells, osteoblastic cells, endothelial cells, myeloid cells (myeloid-derived suppressor cells (MDSCs), tumor-associated macrophages (TAMs), and dendritic cells (DC)), lymphocytes (T cells, B cells and nature killer (NK) cells), bone marrow stromal cells (BMSCs) extracellular matrix (ECM), vasculature, and soluble factors such as growth factors, cytokines, chemokines.