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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: J Allergy Clin Immunol. 2020 Jun 29;147(3):910–920. doi: 10.1016/j.jaci.2020.06.013

Figure 2.

Figure 2.

Overall bacterial (alpha) diversity in relation to asthma, atopy, and hay fever. Richness and Shannon index (H) were calculated using rarefied (minimum number of sequences across samples=8,182) OTU data. Error bars represent 95% confidence interval. Mean (95% CI) of alpha diversity measures by health outcomes are as follows: current asthma – richness 663.74 (654.60-672.89) and Shannon index 4.58 (4.51-4.66) for non-asthmatics, richness 670.35 (660.35-680.36) and Shannon index 4.58 (4.50-4.67) for asthmatics; current atopy – richness 670.02 (661.81-678.23) and Shannon index 4.61 (4.49-4.72) for non-atopics, richness 649.67 (641.18-658.16) and Shannon index 4.48 (4.35-4.6) for atopics; current atopy and asthma – richness 666.90 (657.20-676.60) and Shannon index 4.61 (4.55-4.67) for none, richness 642.30 (615.43-669.17) and Shannon index 4.41 (4.21-4.6) for atopy only, richness 676.22 (661.05-691.39) and Shannon index 4.60 (4.50-4.70) for asthma only, and richness 655.22 (631.4-679.03) and Shannon index 4.53 (4.36-4.69) for both; diagnosed hay fever – richness 671.68 (662.62-680.75) and Shannon index 4.60 (4.55-4.66) for individuals without hay fever, richness 657.20 (644.25-670.15) and Shannon index 4.54 (4.46-4.63) for individuals with hay fever. *indicates p-value<0.1; **indicates p-value<0.05.