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. Author manuscript; available in PMC: 2022 Jan 30.
Published in final edited form as: Stat Med. 2020 Nov 12;40(2):403–426. doi: 10.1002/sim.8781

TABLE 3.

Performance of different methods for synthesizing standardized mean differences based on 10,000 replicates of simulated meta-analyses with N = 20 studies under various settings.

Method τ = 0.1 τ = 0.5
ni = 6–14 ni = 30–70 ni = 6–14 ni = 30–70
Bias RMSE CP, % Bias RMSE CP, % Bias RMSE CP, % Bias RMSE CP, %
θ = 0:
Cohen’s d, Eq. (4) 0.001 0.144 97.7 (95.6) 0.000 0.068 95.2 (95.0) 0.000 0.177 95.4 (95.9) 0.002 0.129 93.4 (95.3)
Cohen’s d, Eq. (5) 0.001 0.144 96.3 (96.1) 0.000 0.068 95.2 (95.0) 0.000 0.178 94.6 (96.4) 0.002 0.129 93.4 (95.3)
Cohen’s d, Eq. (6) 0.001 0.148 95.9 (96.1) 0.000 0.068 95.1 (95.0) −0.001 0.184 94.4 (96.3) 0.002 0.129 93.4 (95.2)
Hedges’ g, Eq. (10) 0.001 0.129 97.7 (95.8) 0.000 0.067 95.2 (95.0) 0.000 0.157 95.6 (96.1) 0.002 0.127 93.4 (95.3)
Hedges’ g, Eq. (11) 0.001 0.129 96.4 (96.2) 0.000 0.067 95.2 (95.0) 0.000 0.159 94.7 (96.5) 0.002 0.127 93.4 (95.2)
Hedges’ g, Eq. (12) 0.001 0.133 95.9 (96.1) 0.000 0.067 95.2 (95.0) −0.001 0.164 94.4 (96.3) 0.002 0.127 93.4 (95.2)
Hedges’ g, Eq. (13) 0.001 0.135 97.0 (95.8) 0.000 0.067 95.3 (95.0) 0.000 0.167 95.1 (95.9) 0.002 0.127 93.4 (95.2)
Hedges’ g, Eq. (14) 0.001 0.128 97.8 (95.8) 0.000 0.067 95.2 (95.0) 0.000 0.157 95.7 (96.1) 0.002 0.127 93.4 (95.3)
Hedges’ g, Eq. (20) 0.001 0.154 95.8 (95.1) [96.5] 0.000 0.069 95.1 (94.7) [95.2] −0.001 0.192 94.1 (95.1) [95.2] 0.002 0.130 93.4 (95.0) [93.5]
Hedges’ g, Eq. (21) 0.001 0.153 96.3 (94.9) [96.2] 0.000 0.069 95.1 (94.7) [95.1] −0.001 0.192 94.3 (94.8) [94.4] 0.002 0.130 93.4 (95.0) [93.5]
Hedges’ g, Eq. (22) 0.001 0.156 94.9 (95.3) [97.2] 0.000 0.069 94.9 (94.8) [95.2] −0.001 0.193 93.9 (95.3) [96.0] 0.002 0.130 93.4 (95.0) [93.6]
θ = 0.3:
Cohen’s d, Eq. (4) −0.012 0.145 97.6 (95.8) −0.001 0.068 95.2 (94.9) −0.023 0.179 95.5 (95.8) −0.003 0.130 93.3 (95.1)
Cohen’s d, Eq. (5) −0.010 0.145 96.3 (96.2) −0.001 0.068 94.9 (94.9) −0.016 0.179 94.7 (96.3) −0.003 0.130 93.3 (95.1)
Cohen’s d, Eq. (6) −0.002 0.148 96.0 (96.1) 0.000 0.069 95.0 (94.9) −0.006 0.184 94.7 (96.2) −0.003 0.131 93.3 (95.1)
Hedges’ g, Eq. (10) −0.042 0.136 96.9 (94.9) −0.006 0.068 95.1 (94.9) −0.051 0.166 94.6 (95.4) −0.008 0.128 93.3 (95.0)
Hedges’ g, Eq. (11) −0.041 0.136 95.2 (95.2) −0.006 0.068 94.9 (94.9) −0.046 0.166 93.9 (95.8) −0.008 0.128 93.3 (95.0)
Hedges’ g, Eq. (12) −0.034 0.137 95.0 (95.5) −0.005 0.068 94.9 (94.9) −0.038 0.169 94.0 (96.0) −0.008 0.129 93.3 (95.0)
Hedges’ g, Eq. (13) −0.029 0.138 96.5 (95.4) −0.005 0.068 95.0 (94.9) −0.035 0.170 94.7 (95.7) −0.008 0.129 93.3 (95.0)
Hedges’ g, Eq. (14) −0.043 0.136 96.9 (94.8) −0.006 0.068 95.1 (94.9) −0.053 0.166 94.6 (95.3) −0.008 0.128 93.3 (95.0)
Hedges’ g, Eq. (20) 0.000 0.155 95.7 (95.2) [96.5] 0.000 0.069 95.0 (94.7) [95.1] −0.001 0.193 94.6 (95.4) [95.6] −0.001 0.131 93.3 (94.9) [93.5]
Hedges’ g, Eq. (21) 0.000 0.154 96.3 (95.2) [96.2] 0.000 0.069 95.0 (94.7) [95.0] −0.002 0.192 94.8 (95.2) [94.9] −0.001 0.131 93.3 (94.9) [93.4]
Hedges’ g, Eq. (22) 0.000 0.157 95.1 (95.3) [97.1] 0.000 0.069 94.8 (94.7) [95.2] −0.002 0.194 94.4 (95.7) [96.3] −0.001 0.131 93.3 (94.9) [93.4]
θ = 0.8:
Cohen’s d, Eq. (4) −0.030 0.152 97.2 (95.3) −0.002 0.070 95.4 (95.0) −0.054 0.191 94.5 (95.1) −0.006 0.131 93.6 (95.3)
Cohen’s d, Eq. (5) −0.023 0.151 95.9 (96.0) −0.002 0.070 95.3 (95.1) −0.037 0.188 94.0 (95.8) −0.005 0.131 93.6 (95.3)
Cohen’s d, Eq. (6) −0.004 0.153 96.0 (96.1) −0.001 0.070 95.2 (95.1) −0.013 0.190 94.3 (96.3) −0.004 0.131 93.6 (95.4)
Hedges’ g, Eq. (10) −0.108 0.171 92.3 (89.2) −0.015 0.071 94.7 (94.4) −0.131 0.209 87.8 (89.5) −0.019 0.130 93.4 (95.2)
Hedges’ g, Eq. (11) −0.105 0.170 89.7 (90.1) −0.015 0.071 94.5 (94.4) −0.118 0.203 87.6 (91.0) −0.019 0.130 93.3 (95.2)
Hedges’ g, Eq. (12) −0.088 0.163 91.1 (91.8) −0.014 0.071 94.6 (94.5) −0.097 0.195 89.8 (92.6) −0.018 0.130 93.4 (95.2)
Hedges’ g, Eq. (13) −0.076 0.158 94.0 (92.6) −0.014 0.071 94.6 (94.5) −0.089 0.193 91.4 (93.0) −0.018 0.130 93.4 (95.2)
Hedges’ g, Eq. (14) −0.111 0.173 92.1 (88.6) −0.015 0.071 94.7 (94.4) −0.135 0.211 87.3 (89.0) −0.019 0.130 93.3 (95.2)
Hedges’ g, Eq. (20) 0.001 0.162 95.7 (95.1) [96.8] 0.001 0.071 95.2 (94.9) [95.4] 0.001 0.200 94.4 (95.3) [95.6] −0.001 0.131 93.5 (95.1) [93.6]
Hedges’ g, Eq. (21) 0.000 0.160 96.4 (94.7) [96.3] 0.001 0.071 95.3 (94.9) [95.3] 0.000 0.199 94.5 (95.0) [94.5] −0.001 0.131 93.4 (95.1) [93.5]
Hedges’ g, Eq. (22) 0.001 0.164 95.0 (95.2) [97.1] 0.001 0.071 95.2 (95.0) [95.5] 0.000 0.201 94.2 (95.4) [96.3] −0.001 0.131 93.5 (95.1) [93.6]

Abbreviation: CP, coverage probability of 95% confidence interval; RMSE, root mean squared error.

Notation: N, no. of studies; τ, between-study standard deviation; ni, study-specific sample size; θ, true overall standardized mean difference.

Note: coverage probabilities include those based on conventional meta-analysis method in Equation (23) (outside parentheses and square brackets), based on the Hartung–Knapp–Sidik–Jonkman method in Equation (24) (inside parentheses), and based on the method in Equation (26) (inside square brackets).