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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Int J Biochem Cell Biol. 2020 Nov 20;130:105885. doi: 10.1016/j.biocel.2020.105885

Fig. 7.

Fig. 7.

TNFAIP8 facilitates glycolytic metabolic profile in PCa PC3 cells. (A) Stable EV and TNFAIP8 expressing PC3 cells were grown in three independent samples, and glucose-related targeted metabolic profiling was analyzed by LC-MS Single Reaction Monitoring (SRM) as described in the materials and methods section and a heat map of differentially regulated key glycolytic metabolites was presented. (B) TNFAIP8 isoform II knockdown PC3 cells were grown in three independent experiments and metabolic profiling was analyzed by LC-MS Single Reaction Monitoring (SRM). The heat map of down-regulated key glycolytic metabolites was presented. (C) The model represents the possible roles of TNFAIP8 in AKT activation, metabolic reprogramming and PCa progression.