TABLE 2.
Changes in body weight as well as serum glucose, triglycerides and total cholesterol levels during induction of HFFD/STZ type 2 diabetes in rats.
| Time | BW (g) | Serum glucose (mg/dL) | Serum TGs (mg/dL) | Serum TC (mg/dL) |
|---|---|---|---|---|
| Start (week 0) | 98.00 ± 4.09 | 81.40 ± 1.80 | 46.38 ± 2.38 | 53.37 ± 0.65 |
| 8th week (HFFD + insulin) | 260.00 ± 6.79* | 123.60 ± 2.69* | 131.80 ± 7.11* | 95.27 ± 5.24* |
| 1 week after STZ | 252.30 ± 2.13* | 316.20 ± 14.60*# | 131.20 ± 8.97* | 87.35 ± 5.49* |
BW: body weight, HFFD: high fat-high fructose diet, STZ: streptozotocin, TC: total cholesterol, TGs: triglycerides. Each value represents the mean of six experiments ±SEM. Statistical analysis was done using One way ANOVA followed by Tukey’s post-hoc test. *p < 0.05 vs. week 0, # p < 0.05 vs. 8th week.