Table 1.

Several examples reflecting diverse roles of Notch pathway in a cell- and cancer-specific manner.

Function of notch in	References
Oncogenic
Blood	Koch and Radtke, 2011a,b
Brain	Fan et al., 2004, p. 2; Purow et al., 2005; Gao et al., 2007; Kanamori et al., 2007; Zhang X.-P. et al., 2008; Gaetani et al., 2010; Zhao et al., 2010
Lungs	Zheng et al., 2013
Breast	Pece et al., 2004; Reedijk et al., 2005; Ayyanan et al., 2006; Hu et al., 2006; Sansone et al., 2007; Shipitsin et al., 2007
Pancreas	Miyamoto et al., 2003; De La O et al., 2008; Plentz et al., 2009; Mazur et al., 2010; Maniati et al., 2011; Cook et al., 2012
Tumor suppressive
Skin	Nicolas et al., 2003; Wang et al., 2011; Pickering et al., 2014
Esophagus	Alcolea et al., 2014; Gao et al., 2014; Song et al., 2014
Lungs	George et al., 2015
Liver	Viatour et al., 2011
Pancreas	Hanlon et al., 2010