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Epitopes of factor H autoantibodies (FHAAs) targeting domains on factor H (FH). Recombinant FH fragments (SCRs) and the mini FH construct are shown above a schematic of FH. Below are shown the epitope mapping results for aHUS (n=49) and C3G (n=19) patients (solid lines = positive FHAA results, dash lines = negative FHAA results).
