Table 1.

Demographic and genetic data for aHUS patients.

Patient	Sex	Age range	Ethnicity	Genetic findings	Copies
aHUS				(rare variant MAF<0.01%)	CFHR3	CFHR1	CFHR4
aHUS1	M	6–10	Caucasian	N/A	N/A	N/A	N/A
aHUS2	M	6–10	Caucasian	no variants	0	0	2
aHUS3	M	11–15	Caucasian	no variants	0	0	2
aHUS4	M	6–10	Caucasian	no variants	1	0	1
aHUS5	F	6–10	Caucasian	N/A	0	0	2
aHUS6	M	6–10	Caucasian	no variants	0	0	2
aHUS7	F	16–20	Caucasian	no variants	0	0	2
aHUS8	F	1–5	Caucasian	no variants	0	0	2
aHUS9	F	6–10	Caucasian	N/A	N/A	N/A	N/A
aHUS10	M	16–20	African American	no variants	0	0	2
aHUS11	M	31–35	Caucasian	no variants	0	0	2
aHUS12	F	6–10	Caucasian	no variants	0	0	2
aHUS13	M	1–5	African American	CFHR5 c.427A>C, p.Thr143Pro	0	0	2
aHUS14	F	6–10	Hispanic	no variants	1	0	1
aHUS15	M	11–15	Caucasian	no variants	0	0	2
aHUS16	M	11–15	Asian	no variants	0	0	2
aHUS17	F	11–15	Hispanic	no variants	0	0	2
aHUS18	M	6–10	Caucasian/African American	no variants	0	0	2
aHUS19	F	6–10	African American	no variants	0	0	2
aHUS20	M	6–10	Hispanic	N/A	N/A	N/A	N/A
aHUS21	F	6–10	Caucasian	CFH c.3644G>A, p.Arg1215Gln	0	0	2
aHUS22	M	11–15	Caucasian	no variants	0	0	2
aHUS23	M	16–20	Caucasian	no variants	0	0	2
aHUS24	M	61–65	Caucasian	no variants	1	0	1
aHUS25	F	11–15	Caucasian	no variants	0	0	2
aHUS26	M	11–15	Arabic	no variants	0	0	2
aHUS27	M	11–15	Caucasian	no variants	1	0	1
aHUS28	M	1–5	Caucasian	no variants	0	0	2
aHUS29	F	11–15	Caucasian	no variants	1	0	1
aHUS30	M	6–10	Hispanic	no variants	0	0	2
aHUS31	F	6–10	Caucasian	no variants	0	0	2
aHUS32	F	41–45	Caucasian	no variants	1	0	1
aHUS33	F	16–20	African American	no variants	0	0	2
aHUS34	F	6–10	Asian	no variants	0	0	2
aHUS35	F	11–15	Asian	N/A	0	0	2
aHUS36	M	6–10	Hispanic	no variants	0	0	2
aHUS37	M	6–10	Caucasian	no variants	0	0	2
aHUS38	M	1–5	African American	no variants	1	1	2
aHUS39	M	46–50	Caucasian	CFH c.3536T>C, p.Ile1179Thr	2	2	2
aHUS40	M	51–55	Caucasian	no variants	2	2	2
aHUS41	M	16–20	Hispanic	no variants	2	2	2
aHUS42	F	6–10	Hispanic	no variants	2	2	2
aHUS43	F	6–10	Caucasian	no variants	2	2	2
aHUS44	F	11–15	Asian	no variants	2	2	2
aHUS45	F	6–10	Hispanic	no variants	2	1	1
aHUS46	M	71–75	Caucasian	no variants	1	1	2
aHUS47	M	16–20	Caucasian	no variants	2	2	2
aHUS48	M	1–5	Arabic	no variants	2	2	2
aHUS49	F	1–5	Caucasian	no variants	N/A	N/A	N/A

N/A, not available.