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. 2020 Dec 15;11:607211. doi: 10.3389/fimmu.2020.607211

Table 4.

FHAAs in patients with C3 glomerulopathy.

Patient FHR1^ FHAA (AU) FH Epitope Mini-FH FHR1 FHR2 M-Spike FHAA
1-6 6-8 8-15 15-18 18-20 IgG subclasses Light chains
C3G1 absent 2990 + + IgG k IgG1 k
C3G2 present 9315 + + IgG1+IgG4 λ+k
C3G3 present 1059 + + IgG4 λ
C3G4 present 13550 + + IgG1+IgG3 λ
C3G5 present 21010 + + IgG k IgG1 k
C3G6 present 1514 + IgG λ IgG1 λ
C3G7 present 39980 + IgG λ IgG3 λ
C3G8# present 555 + + + IgG3 k
C3G9 present 809 + + + IgG3 k
C3G10 present 1017 + IgG1 λ
C3G11 present 869 + + + + + IgG1 λ+k
C3G12 present 759 + + + + IgG k IgG3 k
C3G13* present 1525 + + IgG3 k
C3G14 present 601 + + IgG3 k
C3G15 present 725 + + IgG3 λ
C3G16 present 1697 + + + + + IgG3 λ
C3G17 present 1238 + + + + IgG3 k
C3G18* absent 843 + N/D + IgG3 k
C3G19 present 908 +       + + +   IgG3 k

^Determined by MLPA or the Western if no DNAs.

*C3G13 and C3G18 are positive for C3Nefs.

#C3G8 is also positive for FBAAs.

Blank, negative; N/D, not done.