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. 2020 Dec 15;11:595672. doi: 10.3389/fimmu.2020.595672

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Copyright © 2020 Masum, Ichii, Elewa, Otani, Namba and Kon

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cellular characterization of PCC at 3 and 6 months of age. (A–D) B-cell infiltration (thin arrow) near the blood vessel (arrow) in PCC (dashed area) of MRL and LPR mice kidney at 3 and 6 months of age (IHC). (E–H) T-cell infiltration (thin arrow) near the blood vessel (arrow) in PCC (dashed area) of MRL and LPR mice kidney at 3 and 6 months of age (IHC). (I–L) Macrophage infiltration (thin arrow) near the blood vessel (arrow) in PCC (dashed area) of MRL and LPR mice kidney at 3 and 6 months of age (IHC). (M–P) LYVE1⁺ lymphatic vessels (thin arrow) near the blood vessel (arrow) in PCC (dashed area) of MRL and LPR mice kidney at 3 and 6 months of age (IHC). Bars = 100 µm. PCC, perivascular cellular cluster; IHC, immunohistochemistry.