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. 2020 Dec 15;10:574383. doi: 10.3389/fonc.2020.574383

Figure 4.

Figure 4

Downregulation of SAPCD2 retards the proliferation and anoikis resistance of fibrosarcoma cells in vitro. (A, B) The effect of silencing SAPCD2 on the proliferation rate in HT-1080 and SW684 cells by CCK-8 assay. Each bar represents the mean values ± SD of three independent experiments. *P < 0.05. (C) The effect of silencing SAPCD2 on the colony-forming ability in HT-1080 and SW684 cells by colony formation assay. (D) The effect of silencing SAPCD2 on the anchorage-independent growth ability in HT-1080 and SW684 cells by anchorage-independent growth assays. Each bar represents the mean values ± SD of three independent experiments. *P < 0.05. (E) The effects of SAPCD2 on apoptotic ratio in the indicated fibrosarcoma cells via annexin V-FITC/PI staining. Error bars represent the mean ± S.D. of three independent experiments. *P < 0.05. (F) The effect of SAPCD2 on the invasion ability in the indicated fibrosarcoma cells. Error bars represent the mean ± S.D. of three independent experiments.