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Effect of CBD (100 μM) on the constitutive activity of Gi/o proteins alone and combined with WAY100635 on [35S]-GTPγS binding in cell membranes obtained from the hippocampus (top panel) and temporal neocortex (bottom panel) of autopsies and patients with drug-resistant MTLE. Values are expressed as the mean ± SEM. ***p < 0.001; ****p < 0.0001.
