Table 1.
Demographic and clinical characteristics of the study participants.
| Parameter | Health(n=22) | MAFLD(n=24) | P |
|---|---|---|---|
| Age (years) | 52.91 ± 4.25 | 52.75 ± 4.39 | 0.9013 |
| Sex (M: F) | 11: 11 | 13: 11 | 0.9898 |
| TC (mmol/L) | 5.77± 0.78 | 5.47 ± 0.88 | 0.2254 |
| TG (mmol/L) | 1.55 ± 1.04 | 2.51 ± 1.28 | 0.0083* |
| LDL-C (mmol/L) | 3.41± 0.52 | 3.28± 0.66 | 0.4735 |
| HDL-C (mmol/L) | 1.40 ± 0.36 | 1.10± 0.21 | 0.0011* |
| ALT (U/L) | 22.68 ± 12.99 | 40.25 ± 27.55 | 0.0092* |
| AST (U/L) | 31.5 ± 18.13 | 38.21 ± 19.09 | 0.2292 |
| AST/ALT | 1.52 ± 0.66 | 1.11 ± 0.43 | 0.0142* |
| GGT (U/L) | 24.50 ± 21.16 | 57.42 ± 52.11 | 0.0084* |
| FPG (mmol/L) | 5.01 ± 0.46 | 5.18+0.56 | 0.3196 |
| FSI(mU/L) | 4.02 ± 2.68 | 6.84 ± 2.68 | 0.0015* |
| HOMA-IR | 0.94 ± 0.59 | 1.58 ± 0.66 | 0.0013* |
| Weight (kg) | 62.20 ± 11.75 | 68.23 ± 9.64 | 0.0631 |
| BMI | 24.13 ± 3.00 | 25.79 ± 2.61 | 0.0502 |
| WC(cm) | 81.84 ± 9.45 | 89.79 ± 6.88 | 0.0020* |
| SBP (mm Hg) | 139.00 ± 26.88 | 136.46 ± 19.65 | 0.7144 |
| DBP (mm Hg) | 82.77 ± 14.93 | 82.79 ± 12.17 | 0.9962 |
| HR Periodontitis (%) |
76.09 ± 8.38 81.82 |
73.71 ± 10.25 79.17 |
0.3954 0.8843 |
Data are presented as the mean ± standard deviation. *P < 0.05. All clinical and demographic data were analyzed using the unpaired t-test with an exception of “sex” and “periodontitis”, which were analyzed with the Yates’ continuity corrected χ2 test. Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; DBP, diastolic blood pressure; FPG, fasting plasma glucose; FSI, fasting serum insulin; GGT, gamma glutamyl trans-peptidase; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homeostatic model assessment of insulin resistance [HOMA-IR = FPG (mmol/L) × FSI (mU/L)/22.5]; HR, heart rate; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure; TC, total cholesterol; TG, total triglycerides; WC, waist circumference.