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. 2020 Dec 15;11:604404. doi: 10.3389/fphar.2020.604404

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Copyright © 2020 Yingnan, Gao, Wang, Li, Zhang, Zhu and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effect of oral 1340 mg/d NMN-administration on liver function, kidney function and blood lipids in beagle dogs (A) Body weights were measured before and after NMN administration. (B) Serum NAM levels were increased after NMN administration. (C–E) Liver function was analyzed after NMN administration. (F–H) Kidney function was analyzed after NMN administration. (F) Creatinine was evaluated in 1340 mg/kg/d NMN-administered dogs. (H) Uric acid was evaluated in 1340 mg/kg/d NMN-administered dogs. (I–L) Blood lipids were measured before and after NMN administration.