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. 2020 Oct 23;21(12):3669–3678. doi: 10.1093/pm/pnaa293

Table 5.

Multivariable model of developing chronic opioid use

Odds Ratio P > z 95% Confidence Interval
Age categories, y
18–30 Reference
5–17 0.56 <0.01 0.54 0.57
31–50 1.57 <0.01 1.55 1.58
51–65 1.78 <0.01 1.76 1.80
66–99 1.53 <0.01 1.51 1.55
Sex
Male Reference
Female 1.06 <0.01 1.05 1.07
Missing 1.28 <0.01 1.17 1.41
Payment type
Commercial Reference
Private pay 1.03 <0.01 1.02 1.05
Medicare 1.12 <0.01 1.11 1.14
Medicaid 1.72 <0.01 1.70 1.74
Workers’ compensation 1.95 <0.01 1.84 2.05
Major medical 3.33 <0.01 3.25 3.42
Extended-release
No Reference
Yes 1.79 <0.01 1.74 1.84
Month filled
January Reference
February 0.98 0.03 0.97 1.00
March 0.94 <0.01 0.93 0.96
April 1.04 <0.01 1.02 1.06
May 0.89 <0.01 0.88 0.91
June 0.86 <0.01 0.85 0.88
July 0.84 <0.01 0.83 0.86
August 0.82 <0.01 0.81 0.84
September 0.79 <0.01 0.78 0.81
October 0.75 <0.01 0.74 0.76
November 0.65 <0.01 0.64 0.66
December 0.70 <0.01 0.69 0.71
Year filled
2013 Reference
2014 0.88 <0.01 0.87 0.89
2015 0.60 <0.01 0.60 0.61
2016 0.31 <0.01 0.31 0.32
Prescription morphine milligram equivalents
9–50 Reference
51–100 0.91 <0.01 0.90 0.92
101–150 1.17 <0.01 1.15 1.18
151–200 1.26 <0.01 1.23 1.28
201–250 1.30 <0.01 1.28 1.33
251–300 1.81 <0.01 1.78 1.84
301–350 1.55 <0.01 1.48 1.62
351–400 1.53 <0.01 1.48 1.58
401–450 2.20 <0.01 2.15 2.24
451–500 2.05 <0.01 1.96 2.14
>500 2.90 <0.01 2.85 2.95
Specialty of prescriber
Internal medicine Reference
Ophthalmology 0.33 <0.01 0.3 0.36
Gynecology 0.37 <0.01 0.36 0.38
Dentistry 0.39 <0.01 0.38 0.4
Specialty surgery 0.44 <0.01 0.43 0.45
Dermatology 0.45 <0.01 0.41 0.5
Radiology 0.49 <0.01 0.45 0.53
Psychiatry 0.54 <0.01 0.5 0.58
Other 0.60 <0.01 0.59 0.61
Missing 0.67 <0.01 0.66 0.67
Orthopedics 0.74 <0.01 0.72 0.75
Pediatrics 0.74 <0.01 0.7 0.78
Hematology/oncology 0.78 <0.01 0.73 0.82
Midlevel 0.84 <0.01 0.82 0.86
Emergency medicine 0.85 <0.01 0.84 0.86
Addiction medicine 1.02 0.91 0.76 1.37
Physical medicine 1.29 <0.01 1.24 1.34
Neurology 1.43 <0.01 1.33 1.54
Anesthesiology 1.46 <0.01 1.42 1.51