Table 3.
HRs for major CVD, all-cause mortality, and CV mortality in HIC, MIC, and LIC
| n | HIC | MIC | LIC | |
|---|---|---|---|---|
| Major CVD, n (%) | 498 (3.1) | 3,743 (4.1) | 1,719 (5.4) | |
| Model 1 | 124,067 | 2.13 (1.72–2.64) | 1.92 (1.77–2.09) | 1.94 (1.69–2.22) |
| Model 2 | 106,924 | 1.84 (1.46–2.33) | 1.74 (1.59–1.91) | 1.86 (1.57–2.21) |
| Model 3 | 106,924 | 1.59 (1.17–2.15) | 1.70 (1.52–1.89) | 1.82 (1.50–2.20) |
| All-cause mortality, n (%) | 395 (2.4) | 3,818 (4.2) | 3,378 (10.5) | |
| Model 1 | 124,067 | 1.36 (1.05–1.78) | 1.44 (1.32–1.58) | 1.33 (1.18–1.49) |
| Model 2 | 106,924 | 1.20 (0.90–1.61) | 1.37 (1.24–1.52) | 1.51 (1.31–1.75) |
| Model 3 | 106,924 | 0.99 (0.68–1.45) | 1.18 (1.03–1.34) | 1.40 (1.18–1.66) |
| CV mortality, n (%) | 59 (0.4) | 1,068 (1.2) | 999 (3.1) | |
| Model 1 | 124,067 | 1.84 (1.01–3.37) | 1.64 (1.39–1.94) | 1.89 (1.58–2.27) |
| Model 2 | 106,924 | 1.44 (0.76–2.75) | 1.48 (1.24–1.78) | 1.89 (1.48–2.40) |
| Model 3 | 106,924 | 1.63 (0.76–3.48) | 1.14 (0.90–1.45) | 1.78 (1.36–2.34) |
Data are HR (95% CI) unless otherwise noted. Reference group: individuals without diabetes. Model 1: adjusted for age, sex, ethnicity, and center (as random effect). Model 2: model 1 + behavioral factors (physical activity level, smoking), BMI, and hypertension. Model 3: model 2 + treatments (BP-, cholesterol-, and glucose-lowering agents and aspirin).