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. 2020 Aug 17;43(12):2930–2937. doi: 10.2337/dc20-0553

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© 2020 by the American Diabetes Association

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Sex-specific associations of baseline NT-proBNP concentrations with risk of type 2 diabetes in the case-cohort of the EPIC-Potsdam study (n = 1,656). Adjusted HRs per doubling in NT-proBNP concentrations were assessed with Cox proportional hazards model (main model 2) and are shown with corresponding 95% CIs in the middle of each panel. Linearity of the relationship between NT-proBNP concentrations and risk of type 2 diabetes was assessed with restricted cubic splines. Splines with corresponding 95% CIs from five imputation data sets are shown.