Fig. 1.

AMSCs and EVs derived from mouse adipose tissues. The left in the upper panels are the morphology of Adipose-derived mesenchymal stem cells (AMSC)s derived from the Wild type of mice (BALB/c; WT) and IL-1ra deficient (IL-1ra^−/−) mice. AMSCs are cells attached to a culture dish. The morphologies are at six days after the beginning of their culture. The light in the upper panels are the electron micrograph of the extracellular vesicle (EV)s by negative staining. White particles in the pictures are EVs. The size bar in the pictures is 200 nm. The lower panels are the data for the size and distribution of EVs by nanoparticle tracking analysis with Nano Sight.