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Adipose tissue-derived AMSCs and EVs include IL-1ra. a, Western blot for IL-1ra of AMSCs and EVs are shown. CD63 was used as the loading control of the samples. IL-1ra expression in each sample normalized IL-1ra expression intensity/CD63 expression intensity and then the expression intensity of IL-1ra revealed the intensity of WT-AMSC as 1. b, IL-1ra concentration in sera of AMSCs or EVs administrated mice.
