Fig. 5.

BMSC-derived exosomes regulated cell function of tenocytes through TGF-β1 signaling. A) Cell proliferation of tenocytes was determined by CCK-8 assay for cells treated with BMSC-derived exosomes and LY2108761 or alone. B) Cell cycle of different groups of tenocytes was measured by flow cytometry. C) Cell migration was determined using transwell assay. D) and E) mRNA and protein levels of Col I, Col III, α-SMA, Scx and TnC were determined by qPCR and western blot. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001.