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. 2020 Nov 28;15:285–294. doi: 10.1016/j.reth.2020.11.002

Table 2.

A summary of the advantages of biomaterials

Types of biomaterials Subtypes of biomaterials Authors Advantages or function of biomaterials Ref
Hydrogels - Hoffman et al
  • -

    drug delivery system

  • -

    cell carrier

  • -

    avoiding immune attack on cells

[106,107]
Kim et al
  • -

    filling the morphological defects of tissues

  • -

    forming ecological niches for cell survival

[[108], [109], [110]]
alginate hydrogels Borselli et al
  • -

    continuously releasing myogenic and angiogenic factors

  • -

    promoting cell migration

  • -

    enhancing the contractile force of injured muscle fibers

  • -

    reducing tissue fibrosis

  • -

    self-degradation

[111,112]
GPT hydrogels Hwang et al
  • -

    continuously releasing bFGF

  • -

    promoting neovascularization and activating biological activity of ECs

[113,114]
PRP hydrogels Amable et al
  • -

    continuously releasing cytokines in serum

  • -

    being beneficial to cell survival, migration and differentiation

  • -

    maintaining or stimulating the function of BM-MSCs

[[115], [116], [117], [118], [119], [120]]
hyaluronic acid based photopolymerization hydrogels Rossi et al
  • -

    enriching cell niches

  • -

    promoting the formation of new blood vessels and nerves

[121]
ECM - Wolf et al
  • -

    promoting cell proliferation and differentiation

  • -

    guaranteeing the stability of microenvironment

[122,123]
3D-ECM of skeletal muscle Panyam et al
  • -

    providing a platform for regenerative tissues

  • -

    building a microenvironment similar to the body

  • -

    immune exemption

[99,[124], [125], [126], [127], [128]]
ECM of porcine small intestinal submucosa Mase et al
  • -

    promoting the formation of new muscle fibers

  • -

    immune exemption

[129]
Preformed scaffolds Collagen Liu et al
  • -

    low immunogenicity

  • -

    self-degradation

  • -

    good biocompatibility

[[130], [131], [132]]
synthetic scaffolds with porous structures Kim et al
  • -

    being beneficial to cell colonization

  • -

    promoting neovascularization and myoblast growth

  • -

    self-degradation

  • -

    porous structures and shape diversity

[[133], [134], [135], [136], [137], [138]]
directional aligned electrospun membranes Choi et al
  • -

    promoting myotube growth

  • -

    excellent mechanical properties

[139,140]
Aviss et al
  • -

    absorbing protein from the environment and stimulating myotube growth

[141]
Bian et al
  • -

    improving the myogenic ability of cells and forming longer myotube by imprinting submicron grooves

[[142], [143], [144]]