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. 2020 Dec 11;11:607689. doi: 10.3389/fphar.2020.607689

TABLE 5.

A summary of current erosolized inorganic NP formulations targeting EMT-markers in the literature.

NP API(s) Disease Model(s) Effect Ref.
ZnO2 and SiO2 NPs N/A Fibrosis LX-2 cells Inhibition of N-Cadherin and EMT, elevation of E-Cadherin Peng et al. (2018)
PEG-coated Au NPs Cold plasma Lung cancer T98G + A549 cells Inhibition of PI3K/AKT axis and EMT Kaushik et al. (2016)
TiO2 NPs N/A Lung cancer A549 cells Inhibition of TGF-β and EMT, reduced cell migration Li et al. (2018a)
ZnO nanostructures N/A Lung cancer H460 + MRC5 cells Inhibition of N-Cadherin and EMT Wahab et al. (2016)
Ag NPs Gallic acid Lung cancer A549 cells Inhibition of Vimentin, N-Cadherin, and Snail-1 Sunil Gowda et al., (2018)