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. 2020 Aug 18;23(12):799–810. doi: 10.1093/ijnp/pyaa061

Figure 2.

Figure 2.

The distribution of brain regions with significant differences in the nodal degrees among the groups at P < .05 (corrected). The networks shown here were constructed by averaging the anatomical connection matrices of all healthy controls, with a sparsity threshold of 10%. Post-hoc tests showed that NTSZ patients and CTSZ patients had significant reduced nodal centrality in most of these regions compared with controls. Compared with the RTSZ group, the CTSZ group had significant lower values in right thalamus, right cuneus, and right precentral gyrus. CTSZ, clozapine-treated schizophrenia patients; CUN, cuneus; HC, healthy controls; HIP, hippocampus; IFGtriang, triangular part of inferior frontal gyrus; L, left; MFG, middle frontal gyrus; NTSZ, never-treated schizophrenia patients; ORBinf, orbital part of inferior frontal gyrus; ORBmid, orbital part of middle frontal gyrus; PreCG, precentral gyrus; R, right; RTSZ, risperidone-treated schizophrenia patients; SOG, superior occipital gyrus; THA, thalamus. *P < .05; **P < .01; ***P < .001.