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. 2020 Dec 12;6(4):363. doi: 10.3390/jof6040363

Table 3.

In silico analysis of repressed microRNAs with the highest fold change and some target genes and pathways involved.

miRNA Target Genes Pathways Involved
hsa-miR-6747 PRKX-GNB5-SYK-ITPR2-IL6R-SPIB-FOXO3-SPIC-SRF-UBE2B-TXR-HMGB1-GBP4-TLR10-SLFN13-FPR1-TLR7-BMPR1A-UGGT2-SIGLEC9-DENNDSB-GSR-PAQR7-SGTB-F2-SSR1-RBM43-FCAR-CCS-KCNMB1- 5HT1, 5HT2, 5HT3, 5HT4 receptors; β cell activation; interleukin, corticotropin release; ubiquitin; P38 MAPK; immune system; stimulus response
hsa-miR-3682-3p MYLK-UBA6-TXLNG-SRRT-IL7R Cytokine-mediated inflammation; ubiquitin; immune system; stimulus response
hsa-miR-144-3p CPS1-RAC1-MAP3K4-GNG12-UBE2A-FZD6-SMARCAS-SMAD4-FBXW7-ARIDIA-ARID1B-MYCN-WNT7A-MAP3K4-PTGS2-GNG12-DAB2-ACSL4-PTGS2-DENNDSB-HSPA13-YOD1-TGFB1-IRS1-LEFTY1 Arginine biosynthesis; β cell activation; stress response; T cell activation; cytokine receptor-mediated signaling; ubiquitin; WNT; P38 MAPK; Toll receptor; MYO signaling, histamine H1 and H2; immune response; stimulus response