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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: J Food Biochem. 2020 Oct 12;44(12):e13522. doi: 10.1111/jfbc.13522

FIGURE 8.

FIGURE 8

Schematic presentation of postulated mechanisms by which cold pressed milk thistle oil intake to obese mice lead to marked suppression of inflammatory markers including NOV and TWIST and diminished liver fibrosis markers including MMP2 and MMP9. Additionally, cold press MTO reverses these changes, obesity suppress effect, and thermogenic genes such as (UCP1, PRMD16), mitochondrial respiration as displayed by the increase in oxygen consumption and improving insulin receptor phosphorylation. Hence, intake cold press MTO offers a multifunctional clinical approach for the treatment of Metabolic Syndrome