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. 2020 Feb 22;12:62. doi: 10.1007/s40820-020-0396-4

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Biodistribution of ¹⁸F in different organs and tumors in MDA-MB-231 tumor-bearing mice at different times after the injection. b Tumor uptake of ¹⁸F comparing in MDA-MB-231 and MCF-7 tumor-bearing mice. Biodistribution of Gd³⁺ in different organs, tissues, and tumors. c CCm₂₃₁-UCNPs in the blood, heart, lung, liver, and spleen. d CCm₂₃₁-UCNPs and UCNPs in the liver and spleen. e Tumor uptake of Gd³⁺ in the MDA-MB-231 CCm₂₃₁-UCNPs group, the MDA-MB-231 UCNPs group, and the MCF-7 CCm₂₃₁-UCNPs group. *, **, and *** indicate P < 0.05, P < 0.01, and P < 0.001, respectively. Data points represent mean ± SD (n = 4)