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. 2020 Feb 22;12:62. doi: 10.1007/s40820-020-0396-4

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — In vivo toxicity evaluation. a Mice body-weight-change curves over 30 days after i.v. injection with PBS or PBS containing UCNPs, CCm₂₃₁, and CCm₂₃₁-UCNPs. b–i Blood parameter data. Red blood cells (RBCs), white blood cells (WBCs), platelets (PLT), hemoglobin (HGB), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC). j–l Blood biochemistry data. Alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine transaminase (ALT), creatinine (CRE), and blood urea nitrogen (BUN). m H&E-stained slice images of major organs. The scale bars = 50 μm. The data points represent the mean ± SD (n = 6)